The “IMRaD” structure Scientific research papers follow the structure (Introduction, Methods, Results, and Discussion), abbreviated as IMRaD structure. The IMRaD structure has evolved in the course of twentieth century and is currently the common structure of articles published in scientific journals. However, the arrangement of the IMRaD structure is rarely substituted in some journals as… Continue reading How to structure your scientific research paper
Randomization is the only scientific method that can balance the representation of known and unknown variables. Because the exclusion of non-compliant patients from the analysis is likely to influence the statistical power and the balance between the study groups, the intention-to-treat concept was introduced. Intention to treat analysis depends on the rule that “All randomized,… Continue reading The intention-to-treat analysis
Randomized Controlled Trial (RCTs) is a good experimental design used to examine the effect of an intervention. This scientific design (Randomized controlled trial) was first described by Austin Bradford Hill in 1950s [1–3]. The introduction of RCTs in clinical research inspired governmental drug agencies to amend their conditions, requiring pharmaceuticals to provide results of well-designed… Continue reading “Randomized Controlled Trial” is good but NOT gold-standard!
Culture is the core, dynamic, adaptive life system of beliefs, behaviors, and attitudes that distinguish a specific population (Kagawa-Singer 2011). Recently, understanding cultures of the target population has become an important consideration to close the gaps between populations and eliminate health disparities (Thomas et al. 2004). Population beliefs and habits in diet, exercise, marriage, and… Continue reading How can culture influence Health?
Data sharing; How to maximize scientific benefit and acknowledge original investigators Over the last decade, maximizing scientific benefit from clinical trials has been pronounced as a moral obligation towards research participants who put themselves at risk to benefit the scientific society. Multiple statements have been issued to ensure quality of clinical trial conduct, analysis, and… Continue reading Sharing Clinical Trial Data